sepsis
Medicina
Verbete 1 de 1
substantivo
Contexto: "Multiple factors may be implicated in the etiology of AKI in children with sepsis. The frequency of sepsis-associated AKI has increased; between 10% and over 30% of cases of AKI were due to sepsis and infection."
Fonte: Riyuzo MC, Silveira LV, Macedo CS, Fioretto JR. Predictive factors of mortality in pediatric patients with acute renal injury associated with sepsis. J Pediatr (Rio J). 2017; 93: 28-34.
Fonte: Riyuzo MC, Silveira LV, Macedo CS, Fioretto JR. Predictive factors of mortality in pediatric patients with acute renal injury associated with sepsis. J Pediatr (Rio J). 2017; 93: 28-34.
Termo equivalente: sepsis
Definição: "Sepsis is a multifaceted host response to an infecting pathogen that may be significantly amplified by endogenous factors. Changes in white blood cell count, temperature, and heart rate reflect inflammation, the host response to “danger” in the form of infection or other insults. Recognized to involve early activation of both pro- and anti-inflammatory responses, along with major modifications in nonimmunologic pathways such as cardiovascular, neuronal, autonomic, hormonal, bioenergetic, metabolic, and coagulation, all of which have prognostic significance."
Fonte: Mervyn Singer, MD, et al. The Third International Consensus entries for Sepsis and Septic Shock. JAMA. 2016;315(8):801-810.
Fonte: Mervyn Singer, MD, et al. The Third International Consensus entries for Sepsis and Septic Shock. JAMA. 2016;315(8):801-810.
Definição em português: "Sepse é a resposta do hospedeiro a um patógeno infectante que pode ser significativamente amplificada por fatores endógenos. Alterações na contagem de células brancas do sangue, temperatura e freqüência cardíaca refletem a inflamação, a resposta do hospedeiro ao "perigo" na forma de infecção ou outros insultos. Reconhecido por envolver a ativação precoce de respostas pró e anti-inflamatórias, juntamente com grandes modificações nas vias não imunológicas, como cardiovascular, neuronal, autonômica, hormonal, bioenergética, metabólica e de coagulação, todas com significado prognóstico."
