hyperalgesic priming
Medicina
Verbete 1 de 1
substantivo
Contexto: "We have previously shown that the development of inflammation-induced hyperalgesic priming is PKC-dependent."
Fonte: Elizabeth K. Joseph, David B. Reichling, Jon D. Levine - Shared Mechanisms for Opioid Tolerance and a Transition to Chronic Pain Journal of Neuroscience 31 March 2010, 30 (13) 4660-4666; DOI: 10.1523/JNEUROSCI.5530-09.2010
Fonte: Elizabeth K. Joseph, David B. Reichling, Jon D. Levine - Shared Mechanisms for Opioid Tolerance and a Transition to Chronic Pain Journal of Neuroscience 31 March 2010, 30 (13) 4660-4666; DOI: 10.1523/JNEUROSCI.5530-09.2010
Termo equivalente: iniciação hiperalgésica
Definição: "A long-lasting latent hyperresponsiveness of nociceptors to inflammatory mediators subsequent to an inflammatory or neuropathic insult."
Fonte: Bogen, O., Alessandri-Haber, N., Chu, C., Gear, R. W., & Levine, J. D. (2012). Generation of a pain memory in the primary afferent nociceptor triggered by PKCε activation of CPEB. The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(6), 2018-26.
Fonte: Bogen, O., Alessandri-Haber, N., Chu, C., Gear, R. W., & Levine, J. D. (2012). Generation of a pain memory in the primary afferent nociceptor triggered by PKCε activation of CPEB. The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(6), 2018-26.
Definição em português: "Uma hiper-responsividade de nociceptores para mediadores inflamatórios após uma inflamação ou uma injúria neuropática."